Intracellular delivery compositions
Protein conjugates comprising a protein carrier comprising a plurality of amine groups, a biological payload that interacts with an intracellular target and a linker linking them, wherein at least a portion of the amine groups are bound to a protecting group are provided. Pharmaceutical compositions...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; heb |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | BEN-MOSHE Tehila FREILICH Shay SHULMAN Avidor SAPIR Yair UZAN GUETA Rozi Ravit SHILOVITZKY Orit GOTTFRIED Yossi MANDEL Ilana FAYGENBOIM-ORNAI Rotem EYLON Bat-Hen CHEN ZELTSBURG Lilach HAKIM Motti LEWKOWICZ Ayala |
| description | Protein conjugates comprising a protein carrier comprising a plurality of amine groups, a biological payload that interacts with an intracellular target and a linker linking them, wherein at least a portion of the amine groups are bound to a protecting group are provided. Pharmaceutical compositions comprising the protein conjugates as well as methods of using and producing the protein conjugates are also provided. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_IL312576A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>IL312576A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_IL312576A3</originalsourceid><addsrcrecordid>eNrjZFD2zCspSkxOzckpzUksUkhJzcksSy2qVEjOzy3IL84syczPK-ZhYE1LzClO5YXS3Axybq4hzh66qQX58anFBUDteakl8Z4-xoZGpuZmjsYEFQAATw8l-Q</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Intracellular delivery compositions</title><source>esp@cenet</source><creator>BEN-MOSHE Tehila ; FREILICH Shay ; SHULMAN Avidor ; SAPIR Yair ; UZAN GUETA Rozi Ravit ; SHILOVITZKY Orit ; GOTTFRIED Yossi ; MANDEL Ilana ; FAYGENBOIM-ORNAI Rotem ; EYLON Bat-Hen ; CHEN ZELTSBURG Lilach ; HAKIM Motti ; LEWKOWICZ Ayala</creator><creatorcontrib>BEN-MOSHE Tehila ; FREILICH Shay ; SHULMAN Avidor ; SAPIR Yair ; UZAN GUETA Rozi Ravit ; SHILOVITZKY Orit ; GOTTFRIED Yossi ; MANDEL Ilana ; FAYGENBOIM-ORNAI Rotem ; EYLON Bat-Hen ; CHEN ZELTSBURG Lilach ; HAKIM Motti ; LEWKOWICZ Ayala</creatorcontrib><description>Protein conjugates comprising a protein carrier comprising a plurality of amine groups, a biological payload that interacts with an intracellular target and a linker linking them, wherein at least a portion of the amine groups are bound to a protecting group are provided. Pharmaceutical compositions comprising the protein conjugates as well as methods of using and producing the protein conjugates are also provided.</description><language>eng ; heb</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240701&DB=EPODOC&CC=IL&NR=312576A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240701&DB=EPODOC&CC=IL&NR=312576A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BEN-MOSHE Tehila</creatorcontrib><creatorcontrib>FREILICH Shay</creatorcontrib><creatorcontrib>SHULMAN Avidor</creatorcontrib><creatorcontrib>SAPIR Yair</creatorcontrib><creatorcontrib>UZAN GUETA Rozi Ravit</creatorcontrib><creatorcontrib>SHILOVITZKY Orit</creatorcontrib><creatorcontrib>GOTTFRIED Yossi</creatorcontrib><creatorcontrib>MANDEL Ilana</creatorcontrib><creatorcontrib>FAYGENBOIM-ORNAI Rotem</creatorcontrib><creatorcontrib>EYLON Bat-Hen</creatorcontrib><creatorcontrib>CHEN ZELTSBURG Lilach</creatorcontrib><creatorcontrib>HAKIM Motti</creatorcontrib><creatorcontrib>LEWKOWICZ Ayala</creatorcontrib><title>Intracellular delivery compositions</title><description>Protein conjugates comprising a protein carrier comprising a plurality of amine groups, a biological payload that interacts with an intracellular target and a linker linking them, wherein at least a portion of the amine groups are bound to a protecting group are provided. Pharmaceutical compositions comprising the protein conjugates as well as methods of using and producing the protein conjugates are also provided.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFD2zCspSkxOzckpzUksUkhJzcksSy2qVEjOzy3IL84syczPK-ZhYE1LzClO5YXS3Axybq4hzh66qQX58anFBUDteakl8Z4-xoZGpuZmjsYEFQAATw8l-Q</recordid><startdate>20240701</startdate><enddate>20240701</enddate><creator>BEN-MOSHE Tehila</creator><creator>FREILICH Shay</creator><creator>SHULMAN Avidor</creator><creator>SAPIR Yair</creator><creator>UZAN GUETA Rozi Ravit</creator><creator>SHILOVITZKY Orit</creator><creator>GOTTFRIED Yossi</creator><creator>MANDEL Ilana</creator><creator>FAYGENBOIM-ORNAI Rotem</creator><creator>EYLON Bat-Hen</creator><creator>CHEN ZELTSBURG Lilach</creator><creator>HAKIM Motti</creator><creator>LEWKOWICZ Ayala</creator><scope>EVB</scope></search><sort><creationdate>20240701</creationdate><title>Intracellular delivery compositions</title><author>BEN-MOSHE Tehila ; FREILICH Shay ; SHULMAN Avidor ; SAPIR Yair ; UZAN GUETA Rozi Ravit ; SHILOVITZKY Orit ; GOTTFRIED Yossi ; MANDEL Ilana ; FAYGENBOIM-ORNAI Rotem ; EYLON Bat-Hen ; CHEN ZELTSBURG Lilach ; HAKIM Motti ; LEWKOWICZ Ayala</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_IL312576A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; heb</language><creationdate>2024</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BEN-MOSHE Tehila</creatorcontrib><creatorcontrib>FREILICH Shay</creatorcontrib><creatorcontrib>SHULMAN Avidor</creatorcontrib><creatorcontrib>SAPIR Yair</creatorcontrib><creatorcontrib>UZAN GUETA Rozi Ravit</creatorcontrib><creatorcontrib>SHILOVITZKY Orit</creatorcontrib><creatorcontrib>GOTTFRIED Yossi</creatorcontrib><creatorcontrib>MANDEL Ilana</creatorcontrib><creatorcontrib>FAYGENBOIM-ORNAI Rotem</creatorcontrib><creatorcontrib>EYLON Bat-Hen</creatorcontrib><creatorcontrib>CHEN ZELTSBURG Lilach</creatorcontrib><creatorcontrib>HAKIM Motti</creatorcontrib><creatorcontrib>LEWKOWICZ Ayala</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BEN-MOSHE Tehila</au><au>FREILICH Shay</au><au>SHULMAN Avidor</au><au>SAPIR Yair</au><au>UZAN GUETA Rozi Ravit</au><au>SHILOVITZKY Orit</au><au>GOTTFRIED Yossi</au><au>MANDEL Ilana</au><au>FAYGENBOIM-ORNAI Rotem</au><au>EYLON Bat-Hen</au><au>CHEN ZELTSBURG Lilach</au><au>HAKIM Motti</au><au>LEWKOWICZ Ayala</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Intracellular delivery compositions</title><date>2024-07-01</date><risdate>2024</risdate><abstract>Protein conjugates comprising a protein carrier comprising a plurality of amine groups, a biological payload that interacts with an intracellular target and a linker linking them, wherein at least a portion of the amine groups are bound to a protecting group are provided. Pharmaceutical compositions comprising the protein conjugates as well as methods of using and producing the protein conjugates are also provided.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; heb |
| recordid | cdi_epo_espacenet_IL312576A |
| source | esp@cenet |
| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Intracellular delivery compositions |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T20%3A04%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=BEN-MOSHE%20Tehila&rft.date=2024-07-01&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EIL312576A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |