Inhibitors of hif-2alpha and methods of use thereof

The present disclosure is directed to compounds that are inhibitors of HIF-2α having a structure according to Formula I, and compositions containing those compounds. Methods of using the compounds for the treatment of diseases, disorders, or conditions are also described.

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Bibliographische Detailangaben
Hauptverfasser:	BEATTY Joel Worley, FOURNIER Jeremy, LIU Dongdong, YU Kai, LELETI Manmohan Reddy, HARDMAN Clayton, MATA Guillaume, GAL Balint, POWERS Jay Patrick, ROSEN Brandon Reid, MAILYAN Artur Karenovich, EPPLIN Matthew, LAWSON Kenneth Victor, DREW Samuel Lawrie, PODUNAVAC Ma?a
Format:	Patent
Sprache:	eng ; heb
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present disclosure is directed to compounds that are inhibitors of HIF-2α having a structure according to Formula I, and compositions containing those compounds. Methods of using the compounds for the treatment of diseases, disorders, or conditions are also described.