Treatment of elevated metabolite levels using nanocarriers

A novel nano-carrier system and method include a virus-like particle, and a functional RNA encapsulated inside the virus-like particle. The virus-like particle protects the functional RNA from nuclease degradation in vivo, and the functional RNA maintains its functionality while being encapsulated i...

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Hauptverfasser: ZILBERZWIGE-TAL Shai, GAZIT Ehud, GAZIT Danielle
Format: Patent
Sprache:eng ; heb
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Zusammenfassung:A novel nano-carrier system and method include a virus-like particle, and a functional RNA encapsulated inside the virus-like particle. The virus-like particle protects the functional RNA from nuclease degradation in vivo, and the functional RNA maintains its functionality while being encapsulated inside the virus-like particle. The system and method may be used to modify, reduce, or treat a disease in a subject.