Fused heterocyclic rings as ripk1 inhibitors

Fused heterocyclic rings as ripk1 inhibitors

The invention provides novel substituted heterocyclic rings represented by Formula I, or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of RIPK1 and the therape...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KIM Namhee, KIM Sunjoo, MIN Jiae, SEO Jeongbeob, KANG Hongjun, YANG Inho, PARK Kitae, KIM Minha, HAN Cheolkyu, CHOI Sungmin, KWON Youngeun, YOON Cheolhwan, JEONG Heejin, JEON Seeun, HAN Sangbae, KIM Jinyoung
Format: Patent
Sprache:eng ; heb
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention provides novel substituted heterocyclic rings represented by Formula I, or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of RIPK1 and the therapeutic methods.