Anti-ctla-4 antibody

The present disclosure provides anti-CTLA-4 antibodies and methods of producing and using the antibodies. The present disclosure also provides nucleic acids encoding the anti-CTLA-4 antibodies and host cells containing the nucleic acids. Furthermore, the present disclosure provides polypeptides cont...

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Bibliographische Detailangaben
Hauptverfasser: KOMORI Yasunori, TATSUMI Kanako, IGAWA Tomoyuki, KAWAUCHI Hiroki, HAYASHI Hiroki, MATSUDA Yutaka, HORI Yuji, KAMIMURA Masaki, SUSUMU Hiroaki, KATADA Hitoshi, SHIMIZU Shun
Format: Patent
Sprache:eng ; heb
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Zusammenfassung:The present disclosure provides anti-CTLA-4 antibodies and methods of producing and using the antibodies. The present disclosure also provides nucleic acids encoding the anti-CTLA-4 antibodies and host cells containing the nucleic acids. Furthermore, the present disclosure provides polypeptides containing a variant Fc region containing amino acid alterations in a parent Fc region and methods of producing and using the polypeptides.