Process for the synthesis of substituted tetrahydrofuran modulators of sodium channels

Process for the synthesis of substituted tetrahydrofuran modulators of sodium channels

Provided in this application is a process for making Compound I (I) and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels. Processes for making various intermediate products, and suitable salts thereof, are also provided.

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Bibliographische Detailangaben
Hauptverfasser: PORTELA Mireia Sidera, WIJETHUNGA Tharanga K, EVERITT Simon Robert, CHANGI Shujauddin M, MCTIERNAN Andrew, HARRISON Cristian, EMER Enrico, LEWANDOWSKI Berenice L, DAVIS Christopher John, PANESAR Maninder, SHANAHAN Stephen, O'DONNELL Michael Edward, SOUSA Bruno Artur
Format: Patent
Sprache:eng ; heb
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Beschreibung
Zusammenfassung:Provided in this application is a process for making Compound I (I) and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels. Processes for making various intermediate products, and suitable salts thereof, are also provided.