Co-expression of constructs and immunostimulatory compounds

Co-expression of constructs and immunostimulatory compounds

The present invention relates to vectors, such as DNA plasmids, comprising multiple nucleic acid sequences engineered to be co-expressed as separate molecules. Such separate molecules include a first polypeptide, wherein the first polypeptide comprises a targeting unit that targets antigen-presentin...

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Hauptverfasser: BERSAAS Audun Trygge Haugen, GRANUM Stine, DILLARD Pierre, FREDRIKSEN Agnete Brunsvik
Format: Patent
Sprache:eng ; heb
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator BERSAAS Audun Trygge Haugen
GRANUM Stine
DILLARD Pierre
FREDRIKSEN Agnete Brunsvik
description The present invention relates to vectors, such as DNA plasmids, comprising multiple nucleic acid sequences engineered to be co-expressed as separate molecules. Such separate molecules include a first polypeptide, wherein the first polypeptide comprises a targeting unit that targets antigen-presenting cells, a multimerization unit, such as dimerization unit, and an antigenic unit comprising one or more antigens or parts thereof, and one or more immunostimulatory compounds.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Co-expression of constructs and immunostimulatory compounds
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