Isoindolinone compounds and imaging agents for imaging huntingtin protein

Provided herein are certain isoindolinone compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.

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Bibliographische Detailangaben
Hauptverfasser: CLARK-FREW Daniel, GADOULEAU Elise, DOMINGUEZ Celia, CHEN Xuemei, JOHNSON Peter David, BROWN Christopher John, LIU Longbin, MILLS Matthew Robert, BARD Jonathan
Format: Patent
Sprache:eng ; heb
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Zusammenfassung:Provided herein are certain isoindolinone compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.