Tgf-beta inhibitors and use thereof

The present disclosure provides TGFβ inhibitor therapy for treating immunosuppressive conditions, such as cancer. Methods of predicting and monitoring therapeutic response are disclosed. Related compositions, methods and therapeutic use are also disclosed.

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Bibliographische Detailangaben
Hauptverfasser:	MARTIN Constance, FAUCETTE Ryan, BRUECKNER Christopher, LEE-HOEFLICH Si Tuen
Format:	Patent
Sprache:	eng ; heb
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING
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Beschreibung
Zusammenfassung:	The present disclosure provides TGFβ inhibitor therapy for treating immunosuppressive conditions, such as cancer. Methods of predicting and monitoring therapeutic response are disclosed. Related compositions, methods and therapeutic use are also disclosed.