3,4-dihydro-2,7-naphthyridine-1,6(2h,7h)-diones as mek inhibitors

The invention relates to a method of treating a MEK-associated tumor by administering to a subject in need thereof a therapeutically effective amount of a solid form 8-((2-fluoro-4-(methylthio)phenyl)amino)-2-(2-hydroxyethoxy)-7-methyl-3,4-dihydro-2,7-naphthyridine-1,6(2H,7H)-dione.

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Bibliographische Detailangaben
Hauptverfasser:	BOYS Mark Laurence, KNAPP Ellen Margaret, REN Li, COWDREY Connor James, FULTON Jennifer Lynn, KELLUM Alex Andrew, MORENO David Austin, DAHLKE Joshua Ryan, WITKOS Faith Elizabeth, BLANCHE Sydney Taylor, DOERNER BARBOUR Patrick Michael, CLARK Wesley Dewitt
Format:	Patent
Sprache:	eng ; heb
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to a method of treating a MEK-associated tumor by administering to a subject in need thereof a therapeutically effective amount of a solid form 8-((2-fluoro-4-(methylthio)phenyl)amino)-2-(2-hydroxyethoxy)-7-methyl-3,4-dihydro-2,7-naphthyridine-1,6(2H,7H)-dione.