Directed conjugation technologies

Among other things, the present disclosure provides technologies for site-directed conjugation of various moieties of interest to target agents. In some embodiments, the present disclosure utilizes target binding moieties to provide high conjugation efficiency and selectivity. In some embodiments, p...

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Bibliographische Detailangaben
Hauptverfasser:	BERBASOVA Tetyana, IBEN Lawrence Gerald, VIDAL Christian Marcel, RASTELLI Luca, SPIEGEL David Adam, CUKAN Michael C, ALVAREZ Enrique, VAILL Ada Margaret, WELSCH Matthew Ernest, BUNIN Anna
Format:	Patent
Sprache:	eng ; heb
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Among other things, the present disclosure provides technologies for site-directed conjugation of various moieties of interest to target agents. In some embodiments, the present disclosure utilizes target binding moieties to provide high conjugation efficiency and selectivity. In some embodiments, provided technologies are useful for preparing antibody conjugates.