Il-38-specific antiobodies

This invention relates to antibodies specific for human interleukin-38 (IL-38), including isolated antibodies, or antigen-binding fragments thereof. The antibodies, or antigen-binding fragments thereof, described here partially or fully block, inhibit, or neutralize a biological activity of IL 38. M...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JOHN P. DOWLING, KAREN LUNDGREN, PAVEL A. NIKITIN, MATTHEW K. ROBINSON, BEN HARMAN
Format: Patent
Sprache:eng ; heb
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Beschreibung
Zusammenfassung:This invention relates to antibodies specific for human interleukin-38 (IL-38), including isolated antibodies, or antigen-binding fragments thereof. The antibodies, or antigen-binding fragments thereof, described here partially or fully block, inhibit, or neutralize a biological activity of IL 38. Methods described here relate to inhibiting tumor growth or metastasis in an individual afflicted by tumor growth and/or metastasis.