Methods of generating oligodendrocytes

A method of generating human mature oligodendrocytes is disclosed. The method comprises contacting a cell population which comprises human pre-oligodendrocytes with an inhibitor of the MAPK/ERK pathway under conditions that allow the pre-oligodendrocytes to differentiate into mature oligodendrocytes...

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Bibliographische Detailangaben
Hauptverfasser: BENJAMIN EITHAN REUBINOFF, Etti BEN-SHUSHAN
Format: Patent
Sprache:eng ; heb
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Beschreibung
Zusammenfassung:A method of generating human mature oligodendrocytes is disclosed. The method comprises contacting a cell population which comprises human pre-oligodendrocytes with an inhibitor of the MAPK/ERK pathway under conditions that allow the pre-oligodendrocytes to differentiate into mature oligodendrocytes. Use of the MAPK/ERK pathway inhibitor for treating diseases is also disclosed.