Carboxamide-pyrimidine derivatives and their use as shp2 antagonists

The invention relates to carboxamide-pyrimidine derivatives of the general formula I,or a pharmaceutically acceptable salt thereof, and the use of the compounds of the present invention for the treatment of hyperproliferative diseases and disorders in mammals, especially humans, and pharmaceutical c...

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Hauptverfasser: MUSCH Doreen, BOIVIN Roch, JOHNSON Theresa, JORAND-LEBRUN Catherine, KUMAR Deepak, MOCHALKIN Igor, LINDE Nina
Format: Patent
Sprache:eng ; heb
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Zusammenfassung:The invention relates to carboxamide-pyrimidine derivatives of the general formula I,or a pharmaceutically acceptable salt thereof, and the use of the compounds of the present invention for the treatment of hyperproliferative diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.