Therapies for squamous cell carcinomas

The present invention relates to the field of cancer therapy. Specifically, provided are methods of neoadjuvant therapies or adjuvant therapies to treat squamous cell carcinoma in a subject with a farnesyltransferase inhibitor (FTI) that include determining whether the subject is likely to be respon...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GUALBERTO Antonio, MISHRA Vishnu S, SCHOLZ Catherine Rose
Format: Patent
Sprache:eng ; heb
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Beschreibung
Zusammenfassung:The present invention relates to the field of cancer therapy. Specifically, provided are methods of neoadjuvant therapies or adjuvant therapies to treat squamous cell carcinoma in a subject with a farnesyltransferase inhibitor (FTI) that include determining whether the subject is likely to be responsive to the FTI treatment based on the H-Ras mutant allele frequency.