B-cell activating cd73 antibodies

Provided herein are, inter alia, methods and compositions using and including anti-CD73 antibodies capable of activating B cells, and affecting the redistribution of B cells from lymphoid tissues to lymphoid organs This previously unknown and unique effect of anti-CD73 antibodies may be useful for t...

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Bibliographische Detailangaben
Hauptverfasser: BUGGY Joseph, GRIFFIN Emily Piccione, HOTSON Andrew
Format: Patent
Sprache:eng ; heb
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Beschreibung
Zusammenfassung:Provided herein are, inter alia, methods and compositions using and including anti-CD73 antibodies capable of activating B cells, and affecting the redistribution of B cells from lymphoid tissues to lymphoid organs This previously unknown and unique effect of anti-CD73 antibodies may be useful for the treatment of various indications, for example, enhancing immunity to immunogenic cancers, treating autoimmune disease (e.g., multiple sclerosis), inflammatory diseases, or infectious disease.