N-substituted-dioxocyclobutenylamino-3-hydroxy-picolinamides useful as ccr6 inhibitors

The present invention relates to N-substituted-dioxocyclobutenylamino-3-hydroxy-picolinamide compounds of Formulae (IA and 1B)or a pharmaceutically acceptable salt or hydrate thereof, that inhibit CC chemokine receptor 6 (CCR6), pharmaceutical compositions containing these compounds, and the use of...

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Bibliographische Detailangaben
Hauptverfasser:	DANIEL WEI-SHUNG KUNG, Huixian WU, Ralph Pelton ROBINSON JR, Daniel Copley SCHMITT, Atli THORARENSEN, Rayomand Jal UNWALLA, Andrew Christopher FLICK, Vincent Michael LOMBARDO, MARK EDWARD SCHNUTE, John Isidro TRUJILLO, Philippe Marcel NUHANT, Brian Stephen GERSTENBERGER, James John MOUSSEAU
Format:	Patent
Sprache:	eng ; heb
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to N-substituted-dioxocyclobutenylamino-3-hydroxy-picolinamide compounds of Formulae (IA and 1B)or a pharmaceutically acceptable salt or hydrate thereof, that inhibit CC chemokine receptor 6 (CCR6), pharmaceutical compositions containing these compounds, and the use of these compounds for treating or preventing diseases, conditions, or disorders ameliorated by inhibition of CCR6.