Topical composition comprising calcipotriol, betamethasone, alpha-tocopherol and butylated hydroxyanisole

The present invention relates to a composition for topical application comprising a polyaphron dispersion, the polyaphron dispersion comprising a continuous aqueous phase and at least one discontinuous oil phase,wherein the polyaphron dispersion comprises calcipotriol, betamethasone dipropionate, al...

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Hauptverfasser: LENON Stephen, CRUTCHLEY Nigel, GEORGIOU Michelle, PRAESTEGAARD Morten
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creator LENON Stephen
CRUTCHLEY Nigel
GEORGIOU Michelle
PRAESTEGAARD Morten
description The present invention relates to a composition for topical application comprising a polyaphron dispersion, the polyaphron dispersion comprising a continuous aqueous phase and at least one discontinuous oil phase,wherein the polyaphron dispersion comprises calcipotriol, betamethasone dipropionate, alpha-tocopherol and butylated hydroxyanisole,wherein at least one of said discontinuous oil phase(s) comprises medium chain triglycerides and isopropyl myristate, andwherein the isopropyl myristate and medium chain triglycerides are present in a weight ratio of from 3:1 to 12:1.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Topical composition comprising calcipotriol, betamethasone, alpha-tocopherol and butylated hydroxyanisole
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