Topical composition comprising calcipotriol, betamethasone, alpha-tocopherol and butylated hydroxyanisole

The present invention relates to a composition for topical application comprising a polyaphron dispersion, the polyaphron dispersion comprising a continuous aqueous phase and at least one discontinuous oil phase,wherein the polyaphron dispersion comprises calcipotriol, betamethasone dipropionate, al...

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Bibliographische Detailangaben
Hauptverfasser: LENON Stephen, CRUTCHLEY Nigel, GEORGIOU Michelle, PRAESTEGAARD Morten
Format: Patent
Sprache:eng ; heb
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Beschreibung
Zusammenfassung:The present invention relates to a composition for topical application comprising a polyaphron dispersion, the polyaphron dispersion comprising a continuous aqueous phase and at least one discontinuous oil phase,wherein the polyaphron dispersion comprises calcipotriol, betamethasone dipropionate, alpha-tocopherol and butylated hydroxyanisole,wherein at least one of said discontinuous oil phase(s) comprises medium chain triglycerides and isopropyl myristate, andwherein the isopropyl myristate and medium chain triglycerides are present in a weight ratio of from 3:1 to 12:1.