Anti-egfr antibody drug conjugate formulations

The invention provides a stable formulation comprising an anti-EGFR antibody drug conjugate (ADC), including an anti-EGFR antibody, e.g., antibody 1, conjugated to an auristatin, e.g., MMAF, histidine, a sugar, and a surfactant.

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Bibliographische Detailangaben
Hauptverfasser: KALETA Katharina, KUMAR Vineet, TSCHOEPE Markus
Format: Patent
Sprache:eng ; heb
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Beschreibung
Zusammenfassung:The invention provides a stable formulation comprising an anti-EGFR antibody drug conjugate (ADC), including an anti-EGFR antibody, e.g., antibody 1, conjugated to an auristatin, e.g., MMAF, histidine, a sugar, and a surfactant.