Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof

The invention provides a controlled release oral solid formulation comparing (a) a controlled release component comprising core comprising levodopa and/or an ester of levodopa or salts thereof, wherein the core is coated with a layer of a muco-adhesive polymer coated with a layer of an enteric coate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DING Amy, GUPTA Suneel, HSU Ann, DONG Liang C
Format: Patent
Sprache:eng ; heb
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Beschreibung
Zusammenfassung:The invention provides a controlled release oral solid formulation comparing (a) a controlled release component comprising core comprising levodopa and/or an ester of levodopa or salts thereof, wherein the core is coated with a layer of a muco-adhesive polymer coated with a layer of an enteric coated polymer; and (b) a decarboxylase inhibitor component.