Rnase for improved microbial detection and antimicrobial susceptibility testing

The present invention relates generally to materials and methods for detection of bacteria, and for testing and determination of antibiotic susceptibility of bacteria in specimens of bodily fluid and other samples. The invention also relates to materials and methods for monitoring the physiological...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CHURCHILL Bernard M, MONTI Gabriel K, HAAKE David, HALFORD Colin W, GUSSIN Daniel
Format: Patent
Sprache:eng ; heb
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Beschreibung
Zusammenfassung:The present invention relates generally to materials and methods for detection of bacteria, and for testing and determination of antibiotic susceptibility of bacteria in specimens of bodily fluid and other samples. The invention also relates to materials and methods for monitoring the physiological response of bacteria to antimicrobial agents, and for reducing background and increasing sensitivity of assays that involve the detection and/or measurement of RNA, such as rRNA. The invention provides kits comprising an RNase packaged for use in the methods described herein.