(s)-4-(8-amino-3-(1-but-2-ynoylpyrrolidin-2-yl) imidazo [1,5-a]pyrazin-1-yl)-n-(pyridin-2-yl)benzamide as btk - inhibitor

(s)-4-(8-amino-3-(1-but-2-ynoylpyrrolidin-2-yl) imidazo [1,5-a]pyrazin-1-yl)-n-(pyridin-2-yl)benzamide as btk - inhibitor

The present invention relates to 6-5 membered fused pyridine ring compounds according to formula Ior a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of 6-5 mem...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: STERRENBURG Jan-Gerard, JANS Christiaan Gerardus Johannes Maria, REWINKEL Johannes Bernardus Maria, BARF Tjeerd A, MAN de Adrianus Petrus Antonius, RAAIJMAKERS Hans C.A, WIJKMANS Jacobus C.H.M, OUBRIE Arthur A
Format: Patent
Sprache:eng ; heb
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention relates to 6-5 membered fused pyridine ring compounds according to formula Ior a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of 6-5 membered fused pyridine ring compounds according to formula I in the treatment of Bruton's Tyrosine Kinase (Btk) mediated disorders.