Expec glycoconjugate vaccine formulations

Expec glycoconjugate vaccine formulations

Compositions and methods for inducing an immune response against extra-intestinal pathogenic Escherichia coli (ExPEC) are described. In particular, multivalent vaccines containing O-antigen polysaccharide covalently bound to an exotoxin A of Pseudomonas aeruginosa (EPA) carrier protein that can with...

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Bibliographische Detailangaben
Hauptverfasser: OLGA LABOVITIADI, WOUTER FRANK TONNIS, FRANCESCO DORO, JANIK ADRIAANSEN
Format: Patent
Sprache:eng ; heb
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Beschreibung
Zusammenfassung:Compositions and methods for inducing an immune response against extra-intestinal pathogenic Escherichia coli (ExPEC) are described. In particular, multivalent vaccines containing O-antigen polysaccharide covalently bound to an exotoxin A of Pseudomonas aeruginosa (EPA) carrier protein that can withstand multiple environmental stresses are describe.