PREPARATION OF INSULIN OLIGOMER CONJUGATES

The present invention discloses a process for making an insulin-oligomer conjugate as a one-pot reaction by conjugation of insulin-ester with an activated oligomer wherein simultaneous deblocking and conjugation is carried out.

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Bibliographische Detailangaben
Hauptverfasser: PARTHA HAZRA, H.S. MANJUNATH, HARISH IYER, GAUTAM KRISHNAN, SHRIKUMAR SURYANARAYAN, ANAND KHEDKAR, NITESH DAVE
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention discloses a process for making an insulin-oligomer conjugate as a one-pot reaction by conjugation of insulin-ester with an activated oligomer wherein simultaneous deblocking and conjugation is carried out.