A POLYPEPTIDE CONTAINING THE GAFA DOMAIN AND THE GAFB DOMAIN OF A HUMAN PHOSPHODIESTERASE

A POLYPEPTIDE CONTAINING THE GAFA DOMAIN AND THE GAFB DOMAIN OF A HUMAN PHOSPHODIESTERASE

The invention relates to a novel polypeptide, containing the GAFA domain and GAFB domain of a human phosphodiesterase 10 (PDE10) and the catalytic domain of an adenylate cyclase and to the use of said polypeptide in a method for identifying PDE10 modulators.

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Sprache:eng
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Zusammenfassung:The invention relates to a novel polypeptide, containing the GAFA domain and GAFB domain of a human phosphodiesterase 10 (PDE10) and the catalytic domain of an adenylate cyclase and to the use of said polypeptide in a method for identifying PDE10 modulators.