Process for the preparation of diphenylmethylthioacetamide

Process for the preparation of diphenylmethylthioacetamide

The invention provides a process for the preparation of diphenylmethylthioacetamide (I) as described in Scheme 4 comprising reacting of the isothiouronium salt or its corresponding base of the formula IV with an acetamide of the formula XCH2CONH2, wherein X represents a halogen, M represents an alka...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JOSEPH KASPI, JAEL LEXNER, SHADI SAEED, VLADIMIR NADAKA, ROI LERMAN, NAIM MENASHE
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention provides a process for the preparation of diphenylmethylthioacetamide (I) as described in Scheme 4 comprising reacting of the isothiouronium salt or its corresponding base of the formula IV with an acetamide of the formula XCH2CONH2, wherein X represents a halogen, M represents an alkali metal and A represents an anion, in a protic medium at a temperature of less than 100 DEG C.