ERYTHROMYCIN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM

ERYTHROMYCIN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM

Erythromycin derivatives of formula (I) and their acid addition salts are new. X = CH2, SO2 or O; Y = (CH2)m(CH=CH)n(CH2)o; m+n+o is \~ 8 and n = 0 or 1; Ar = optionally substituted aryl; W = H or C(O)NHR''; R'' = 1-8C alkyl, or optionally substituted aryl; and Z = H or an acid r...

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Bibliographische Detailangaben
Hauptverfasser: JEAN-FRANCOIS CHANTOT, CONSTANTIN AGOURIDAS
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Beschreibung
Zusammenfassung:Erythromycin derivatives of formula (I) and their acid addition salts are new. X = CH2, SO2 or O; Y = (CH2)m(CH=CH)n(CH2)o; m+n+o is \~ 8 and n = 0 or 1; Ar = optionally substituted aryl; W = H or C(O)NHR''; R'' = 1-8C alkyl, or optionally substituted aryl; and Z = H or an acid residue.