2-substituted quinolines processes for their preparation and their use in medicaments

2-substituted quinolines of the general formula The title compounds are prepared by reacting either the corresponding halomethylquinolines with substituted phenols, then optionally alkylating these and hydrolysing esters to acids, or by reacting phenyl-substituted quinolinecarboxylic acid derivative...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: KLAUS-HELMUT MOHRS, MICHAEL MATZKE, REINER MULLER-PEDDINGHAUS, PIA THEISEN-POPP, ARMIN HATZELMANN, ROMANIS FRUCHTMANN, CHRISTIAN KOHLSDORFER, SIEGFRIED RADDATZ
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:2-substituted quinolines of the general formula The title compounds are prepared by reacting either the corresponding halomethylquinolines with substituted phenols, then optionally alkylating these and hydrolysing esters to acids, or by reacting phenyl-substituted quinolinecarboxylic acid derivatives with sulphonamides. The novel phenyl-substituted quinolines can be used as active compounds in medicaments, in particular as lipoxygenase inhibitors.