2-substituted quinolines processes for their preparation and their use in medicaments
2-substituted quinolines of the general formula The title compounds are prepared by reacting either the corresponding halomethylquinolines with substituted phenols, then optionally alkylating these and hydrolysing esters to acids, or by reacting phenyl-substituted quinolinecarboxylic acid derivative...
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Format: | Patent |
Sprache: | eng |
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Zusammenfassung: | 2-substituted quinolines of the general formula The title compounds are prepared by reacting either the corresponding halomethylquinolines with substituted phenols, then optionally alkylating these and hydrolysing esters to acids, or by reacting phenyl-substituted quinolinecarboxylic acid derivatives with sulphonamides. The novel phenyl-substituted quinolines can be used as active compounds in medicaments, in particular as lipoxygenase inhibitors. |
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