11beta-phenyl-14betaH steroids

PCT No. PCT/EP89/01090 Sec. 371 Date Mar. 20, 1991 Sec. 102(e) Date Mar. 20, 1991 PCT Filed Sep. 20, 1989 PCT Pub. No. WO90/03385 PCT Pub. Date Apr. 5, 1990.New 11 beta -phenyl-14 beta H-steroids of general formula (I), where Z is an oxygen atom or the hydroxyimino-grouping N DIFFERENCE OH, and M an...

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Hauptverfasser: OTTOW ECKHARD DR, BEIER SYBILLE DR, SCHOLZ STEFAN DR, ELGER WALTER DR, CHWALISZ KRZYSZTOF DR, NEEF GUNTER DR
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Sprache:eng
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Zusammenfassung:PCT No. PCT/EP89/01090 Sec. 371 Date Mar. 20, 1991 Sec. 102(e) Date Mar. 20, 1991 PCT Filed Sep. 20, 1989 PCT Pub. No. WO90/03385 PCT Pub. Date Apr. 5, 1990.New 11 beta -phenyl-14 beta H-steroids of general formula (I), where Z is an oxygen atom or the hydroxyimino-grouping N DIFFERENCE OH, and M and N are either jointly a second compound or L is a hydrogen atom and M is an alpha -permanent hydroxy group and either A and B together are a second compound and D is a hydrogen atom, where R1 is a five or six-part heteroalkyl residue or a cycloalkyl, cycloalkenyl or aryl residue or A is a hydrogen atom and B and D together are a methylene bridge, where R1 besides the aforementioned residues may be a possibly substituted hydrocarbon residue with up to 10 C atoms, a possibly substituted amino group, a hydroxy or C1-8 alkoxy, mercapto or thioalkyl group, R2 is a methyl or ethyl residue, and R3/R4 represents the usual combination of substituents on the C17 atom in steroid chemistry, having antigestagenic and other properties.