DTPA Monoamides pharmaceutical agents containing these compounds their use and process for their production

Compounds of the general formula I in which Z and Z in each case represent a hydrogen atom or the radical -(CH2)m-(C6H4)q-(O)k-(CH2)n-(C6H4) l-(O)r-R, in which m and n denote the figures 0-20, k, l, q and r denote the figures 0 and 1 and R denotes a hydrogen atom, an optionally OR -substituted C1-C6-alkyl radical or a CH2COOR group where R denotes a hydrogen atom, a C1-C6-alkyl radical or a benzyl group, R represents a saturated, unsaturated, straight- or branched-chain or cyclic alkyl group having up to 20 C atoms, aryl group or aralkyl group substituted by a carboxyl group optionally esterified with a C1-C6-alkyl or benzyl radical, or by a sulphone group, R represents a hydrogen atom or a saturated, unsaturated, straight- or branched-chain or cyclic alkyl group having up to 20 C atoms, aryl group or aralkyl group optionally substituted by a carboxyl group which is optionally esterified with a C1-C6-alkyl or benzyl radical, or by a sulphone group, X represents a hydrogen atom and/or a metal ion equivalent of an element of atomic number 21-29, 31, 32, 37-40, 42-44, 49 or 57-83, with the proviso that at least one of the substituents Z and Z represents a hydrogen atom, that - when n and l each represent the figure 0 - k and r do not simultaneously each denote the figure 1 and that, if desired, the radical of the acid groups is present as an ester or amide, and their salts with inorganic and/or organic bases, amino acids or amino acid amides, are useful pharmaceutical agents.y