Novel organic nitrates and processes for their preparation

Organic nitrates with a specific structure, consisting of nitrato fatty acids (nitratoalkanoic acids) and sulphur-containing amino acids or peptides, of the general formula in which the symbols have the meanings specified in the claims. Because of the general structural principle - presence of sulph...

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Bibliographische Detailangaben
Hauptverfasser: HUTTER JOACHIM, NOACK EIKE, SANDROCK KLAUS
Format: Patent
Sprache:eng
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Zusammenfassung:Organic nitrates with a specific structure, consisting of nitrato fatty acids (nitratoalkanoic acids) and sulphur-containing amino acids or peptides, of the general formula in which the symbols have the meanings specified in the claims. Because of the general structural principle - presence of sulphhydryl groups - they prevent nitrate tolerance or attenuate a tolerance which has already occurred. The compounds are used in medicaments for treating circulatory disorders, high blood pressure, heart failure and for dilating peripheral vessels.