Novel organic nitrates and processes for their preparation
Organic nitrates with a specific structure, consisting of nitrato fatty acids (nitratoalkanoic acids) and sulphur-containing amino acids or peptides, of the general formula in which the symbols have the meanings specified in the claims. Because of the general structural principle - presence of sulph...
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Zusammenfassung: | Organic nitrates with a specific structure, consisting of nitrato fatty acids (nitratoalkanoic acids) and sulphur-containing amino acids or peptides, of the general formula in which the symbols have the meanings specified in the claims. Because of the general structural principle - presence of sulphhydryl groups - they prevent nitrate tolerance or attenuate a tolerance which has already occurred. The compounds are used in medicaments for treating circulatory disorders, high blood pressure, heart failure and for dilating peripheral vessels. |
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