KARBOKSAMIDOTIAZOL TERSUBSTITUSI, PEMBUATANNYA DAN KOMPOSISI FARMASI YANG MENGANDUNGNYA

KARBOKSAMIDOTIAZOL TERSUBSTITUSI, PEMBUATANNYA DAN KOMPOSISI FARMASI YANG MENGANDUNGNYA

The present invention relates to cholecystokinin (CCK)-agonist substituted thiazoles of formula:in which R1 is a substituted phenyl group, R2 is a group chosen from CH2-R7, (CH2)2-R7, S-CH2-R7, CH2-S-R7 and (C5-C8)alkyl with R7 being a (C5-C7)cycloalkyl group, and R3 is a groupwith R8 being a group...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JEANARLES MOLIMARD, ROBERT BOIGEGRAIN, DOMINIQUE OLLIERO, ERIC BIGNON, ROGER BRODIN
Format: Patent
Sprache:ind
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to cholecystokinin (CCK)-agonist substituted thiazoles of formula:in which R1 is a substituted phenyl group, R2 is a group chosen from CH2-R7, (CH2)2-R7, S-CH2-R7, CH2-S-R7 and (C5-C8)alkyl with R7 being a (C5-C7)cycloalkyl group, and R3 is a groupwith R8 being a group (CH2)nR15 orand R15 being COOH or COO(C1-C4)alkyl. The invention also relates to a process for the preparation of the pharmaceutical compositions containing them and to their uses for the preparation of medicines.