FORMULASI-FORMULASI INSULIN YANG STABIL

The present invention provides a monomeric insulin analog formulation stabilized against aggregation in which the buffering agent is either TRIS or arginine. The stable formulations of the present invention are useful for treating diabetes, and are particularly advantageous in treatment regimes requ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	SHUN LI, BRUCE HILL FRANK, DAWN MARIE REBHUN, MICHAEL ROSARIO DEFELIPPIS, MICHAEL ALIEN DOBBINS
Format:	Patent
Sprache:	ind
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a monomeric insulin analog formulation stabilized against aggregation in which the buffering agent is either TRIS or arginine. The stable formulations of the present invention are useful for treating diabetes, and are particularly advantageous in treatment regimes requiring lengthy chemical and physical stability, such as, in continuous infusion systems.