PHARMACEUTICAL COMPOSITIONS FOR INHIBITING THE EFFECTS OF AMYLOIDOGENIC PROTEINS CONTAINING BENZOTIOPHENE DERIVATIVES AND PROCESS FOR THEIR PREPARATION

This invention encompasses methods for the inhibition of a physiological disorder associated with amyloidogenic proteins, which method comprises administering to a human in need thereof an effective amount of a compound of Formula I wherein R and R are independently hydrogen, -CH3, or wherein Ar is...

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Bibliographische Detailangaben
1. Verfasser:	LUNN,WILLIAM HENRY WALKER
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention encompasses methods for the inhibition of a physiological disorder associated with amyloidogenic proteins, which method comprises administering to a human in need thereof an effective amount of a compound of Formula I wherein R and R are independently hydrogen, -CH3, or wherein Ar is optionally substituted phenyl; R is selected from the group consisting of pyrrolidine, hexamthylenemino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.