EXTERNAL PREPARATIONS CONTAINING CYCLOSPORIN AND PROCESS FOR PRODUCTION OF THEM

An external preparation containing cyclosporin as the active ingredient, characterized by comprising (a) cyclosporin, (b) an organic solvent for dissolving the same, (c) a fatty acid ester of a monohydric alcohol, which is liquid at 25 DEG C and bears at least 8 carbon atoms in total, and/or an alka...

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Hauptverfasser: MIZUSHIMA,YUKATA, NISHIMURA,TATEO, YANAGAWA,AKIRA, KOMIYA,KATSUO, TAKENAGA,MITSUKO, KUDO,TOSHITAKA, IGARASHI,RIE, ANDO,KUNIO
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creator MIZUSHIMA,YUKATA
NISHIMURA,TATEO
YANAGAWA,AKIRA
KOMIYA,KATSUO
TAKENAGA,MITSUKO
KUDO,TOSHITAKA
IGARASHI,RIE
ANDO,KUNIO
description An external preparation containing cyclosporin as the active ingredient, characterized by comprising (a) cyclosporin, (b) an organic solvent for dissolving the same, (c) a fatty acid ester of a monohydric alcohol, which is liquid at 25 DEG C and bears at least 8 carbon atoms in total, and/or an alkanolamine which is liquid at 25 DEG C, (d) an oleaginous substance which is solid at 25 DEG C, and (e) a surfactant, wherein the cyclosporin content ranges from 0.1 to 10 wt.% and the content of the ester and/or alkanolamine ranges from 1 to 15 wt.%. The preparation has an excellent efficacy of curing atopic dermatitis, psoriasis, allergic contact dermatitis, and so forth.
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subjects CHEMISTRY
COMPOSITIONS BASED THEREON
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
POLYSACCHARIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
THEIR PREPARATION OR CHEMICAL WORKING-UP
title EXTERNAL PREPARATIONS CONTAINING CYCLOSPORIN AND PROCESS FOR PRODUCTION OF THEM
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