EXTERNAL PREPARATIONS CONTAINING CYCLOSPORIN AND PROCESS FOR PRODUCTION OF THEM

An external preparation containing cyclosporin as the active ingredient, characterized by comprising (a) cyclosporin, (b) an organic solvent for dissolving the same, (c) a fatty acid ester of a monohydric alcohol, which is liquid at 25 DEG C and bears at least 8 carbon atoms in total, and/or an alka...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	MIZUSHIMA,YUKATA, NISHIMURA,TATEO, YANAGAWA,AKIRA, KOMIYA,KATSUO, TAKENAGA,MITSUKO, KUDO,TOSHITAKA, IGARASHI,RIE, ANDO,KUNIO
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS POLYSACCHARIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	An external preparation containing cyclosporin as the active ingredient, characterized by comprising (a) cyclosporin, (b) an organic solvent for dissolving the same, (c) a fatty acid ester of a monohydric alcohol, which is liquid at 25 DEG C and bears at least 8 carbon atoms in total, and/or an alkanolamine which is liquid at 25 DEG C, (d) an oleaginous substance which is solid at 25 DEG C, and (e) a surfactant, wherein the cyclosporin content ranges from 0.1 to 10 wt.% and the content of the ester and/or alkanolamine ranges from 1 to 15 wt.%. The preparation has an excellent efficacy of curing atopic dermatitis, psoriasis, allergic contact dermatitis, and so forth.