PROCESS FOR PRODUCING SATURATED HYDROXYALKYLQUINOLINE ACIDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS AS ACTIVE INGREDIENT

Compounds having the formula I: are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis,...

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Hauptverfasser: LEGER,SERGE,CA, XIANG,YI BIN,CA, BELLEY,MICHEL L.,CA, LABELLE,MARC,CA, ROY,PATRICK,CA
Format: Patent
Sprache:eng
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Zusammenfassung:Compounds having the formula I: are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.