PROCESS FOR PRODUCING NEW 8-SUBSTITUTED 2-AMINO-TETRALINES AND PHARMACEUTICAL COMPOSITIIONS CONTAINING THEM

A compound of the formula Z is hydrogen or halogen, Q is COR or 5- or 6-membered aryl which may contain 1 or 2 heteroatoms selected from N, O or S and may be substituted or fused wherein R is hydrogen or C1-methyl (cis-configuration), R is C1-C6 alkyl or an aromatic ring which may contain heteroatom...

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Hauptverfasser: BJOERK,ANNA LENA MARIA,SE, ANDEN,NILS-ERIK,SE, VALLGARDA,KARL JERK,SE, PERSSON,EVA MARIE,SE, LIU,YE,SE, MELLIN,EVA CHARLOTTA,SE, YU, HONG,SE, HILLVER,SVEN ERIK,SE, HACKSELL,ULI ALF,SE, BACKLUND,HOEOEK BERIT CHRISTINA ELISABET,SE
Format: Patent
Sprache:eng
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Zusammenfassung:A compound of the formula Z is hydrogen or halogen, Q is COR or 5- or 6-membered aryl which may contain 1 or 2 heteroatoms selected from N, O or S and may be substituted or fused wherein R is hydrogen or C1-methyl (cis-configuration), R is C1-C6 alkyl or an aromatic ring which may contain heteroatoms selected from O and S and may be substituted or fused to an optionally substituted benzene ring, R is hydrogen or C1-C6 alkyl and R may be different groups defined in claim 1, and enantiomers/salts thereof, processes for preparation of said compounds, pharmaceutical preparations containing said compounds, use of and method of treatment of disorders in CNS by using said compounds.