PROCESS FOR RACEMIZING (HALOGEN-ARYL)-ALKYL-AMINES

PROCESS FOR RACEMIZING (HALOGEN-ARYL)-ALKYL-AMINES

Optically active (halo-aryl)-alkyl-amines of general formula (I) (where R = tri:halo-methyl gp.; R1 and R2 are independently hydrogen atom or 1-5C straight or branched alkyl gps.) are racemised by converting them to N-halo cpds. using a halogenating agent of formula (II) (where X = chlorine or bromi...

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Bibliographische Detailangaben
Hauptverfasser: SZINNYEI,EVA,HU, KISS GYULANE AJZERT,ILONA,HU, MOZSOLITS,KAROLY,HU, TOEROEK,ZOLTAN,HU, TAKACS,KALMAN,HU
Format: Patent
Sprache:eng
Schlagworte:
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Optically active (halo-aryl)-alkyl-amines of general formula (I) (where R = tri:halo-methyl gp.; R1 and R2 are independently hydrogen atom or 1-5C straight or branched alkyl gps.) are racemised by converting them to N-halo cpds. using a halogenating agent of formula (II) (where X = chlorine or bromine atom). The N-halogen cpds. are dehydro-halogenated to Schiff bases of formula (III), which on redn. yield racemic cpds. of formula (I)