PROCESS FOR PRODUCING 2-(1-PIPERAZINYL)-4-PHENYL CYCLOALKANOPYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS AS ACTIVE INGREDIENT
Novel 2-(1-piperazinyl)-4-phenyl-cycloalkanopyridine derivatives of the formula (I): wherein n is 3, 4, 5, 6 or 7; R is hydrogen atom, C1-C10 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C3-C6 cycloalkyl-(C1-C4) alkyl, hydroxy-(C2-C6) alkyl, C1-C3 alkoxy-(C2-C6) alkyl, acyloxy-(C2-C6) alky...
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Format: | Patent |
Sprache: | eng |
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Zusammenfassung: | Novel 2-(1-piperazinyl)-4-phenyl-cycloalkanopyridine derivatives of the formula (I): wherein n is 3, 4, 5, 6 or 7; R is hydrogen atom, C1-C10 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, C3-C6 cycloalkyl-(C1-C4) alkyl, hydroxy-(C2-C6) alkyl, C1-C3 alkoxy-(C2-C6) alkyl, acyloxy-(C2-C6) alkyl, unsubstituted or substituted aroyl-(C1-C6) alkyl, unsubstituted or substituted aryl, heteroaryl, or acyl; R and R are the same or different and are each hydrogen atom, halogen atom, C1-C6 alkyl, C1-C6 alkoxy, trifluoromethyl, or hydroxy; R , R and R are the same or different and are each hydrogen atom, C1-C6 alkyl, or phenyl, or two of R , R and R combine to form a single bond or C1-C3 alkylene; R and R are the same or different and are each hydrogen atom or C1-C3 alkyl; m is 2 or 3, or an acid addition salt thereof, which is useful as a psychotropic drug, and processes for the preparation thereof. |
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