PROCESS FOR PRODUCTION OF SMALL PEPTIDES LINKED TO 1,4 RECEPTORS WITH IMMUNOGENE EFFECT AND MEDICAL PREPARATIVES CONTAINING THESE SUBSTANCES

Short peptide of formula (I): R-Ser-Thr-Thr-Thr-Asn-Tyr-R where R represents an amino terminal residue Ala- or D-Ala and R representes a carboxy terminal residue -Thr or -Thr amide or a derivative thereof with an additional Cys- residue at one or both of the amino and carboxy terminals, or a peptide...

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Bibliographische Detailangaben
Hauptverfasser:	RUFF,MICHAEL R.,US, FARRAR,WILLIAM L.,US, PERT,CANDACE B.,US
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Short peptide of formula (I): R-Ser-Thr-Thr-Thr-Asn-Tyr-R where R represents an amino terminal residue Ala- or D-Ala and R representes a carboxy terminal residue -Thr or -Thr amide or a derivative thereof with an additional Cys- residue at one or both of the amino and carboxy terminals, or a peptide of formula (II): R -R -R -R -R where R is an amino terminal residue Thr-, Ser-, Asn-, Leu-, Ile-, Arg- or Glu-, R is Thr, Ser or Asp, R is Thr, Ser, Asn, Arg, Gln, Lys or Trp, R is Tyr and R is a carboxy terminal amino group or a derivative thereof with a corresponding D- amino acid as the amino terminal residue and/or a corresponding amide derivative at the carboxy terminal residue and/or additionally a Cys- residue at one or both of the amino and carboxy terminals, or a physiologically acceptable salt thereof. Such peptides bind to T4 receptors are useful in preventing viral infectivity by viruses which bind to the T4 receptors. These peptides are believed to act as competitive blocking agents.