PROCESS FOR PRODUCING ANTRACYCLIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AS ACTIVE COMPONENTS

PROCESS FOR PRODUCING ANTRACYCLIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AS ACTIVE COMPONENTS

The anthracycline derivatives have the formula I in which R1 and R2 are different and are the sugar residue Roa (L-rhodosamine) of the formula or the sugar combination -Roa-dF = D-Cin B (Roa: L-rhodosamine; dF: 2-deoxy-L-fucose; D-Cin B: D-Cinerulose B) of the formula III and they and their pharmace...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BERSCHEID,HANS G.,DE, FEHLHABER,HANS-WOLFRAM,DE
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Beschreibung
Zusammenfassung:The anthracycline derivatives have the formula I in which R1 and R2 are different and are the sugar residue Roa (L-rhodosamine) of the formula or the sugar combination -Roa-dF = D-Cin B (Roa: L-rhodosamine; dF: 2-deoxy-L-fucose; D-Cin B: D-Cinerulose B) of the formula III and they and their pharmaceutically acceptable acid addition salts have cytostatic effects and can therefore be used as drugs.