PROCESS FOR PRODUCING 2,6-DIALKYL-N-/ALKOXYMETHYL/-CHLOROACETANILIDE DERIVATIVES

PROCESS FOR PRODUCING 2,6-DIALKYL-N-/ALKOXYMETHYL/-CHLOROACETANILIDE DERIVATIVES

2,6-di:alkyl-azo- methine reacts with acetyl-chloride in an aprotic solvent pref. xylene, at 65-75 deg.C. 2,6-di:alkyl-N- chloro-methyl-chloro -acetanilide formed is purified by distn. at 100 deg.C max. pref. at 90 deg.C max. at 1000 Pe pressure, or by crystallisation at a min. of -20 deg.C pref. -5...

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Hauptverfasser: BARCZA,IMRENE,HU, SZIGETI,ISTVAN,HU, DAMJAN,JANOS,HU, SOEPTEI,CSABA,HU, PELYVA,JENOE,HU, HUSZAK,GYOERGY,HU, KOLONICS,ZOLTAN,HU
Format: Patent
Sprache:eng
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Zusammenfassung:2,6-di:alkyl-azo- methine reacts with acetyl-chloride in an aprotic solvent pref. xylene, at 65-75 deg.C. 2,6-di:alkyl-N- chloro-methyl-chloro -acetanilide formed is purified by distn. at 100 deg.C max. pref. at 90 deg.C max. at 1000 Pe pressure, or by crystallisation at a min. of -20 deg.C pref. -5 deg.C. The purified intermediate reacts with alcohol in a 1:3-1:6 (pref.1:4) molar ratio, in the presence of 0.5-1.5 (pref. 1) mol urea. 2,6-di:alkyl-acetanilide is obtd. and washed with water. A weak alkali, pref. 1 wt.% sodium carbonate is added and solvent present is removed by steam distillation at reduced pressure at 120 (pref. 110) deg.C max.