PROCESS FOR PRODUCING NEW ANTIALLERGIC AND ANTITHROMBOTICHETEROCYCLIC COMPOUNDS

Heterocycles of formula (I) and their pharmaceutically acceptable salts are new, Z = N W =CHR2 when n = 0 or CR2 or CHR2 when n = 1; Y = CH2O, OCH2, CH2S, SCH2, CH2N(R2), N(R2)CH2, CON(R2) or N(R2)CO; n = 0 or 1; R1 = H, lower alkyl, lower alkoxy, lower alkanoyl, halo, CF3, NO2 or CN; R2 = H or lowe...

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Hauptverfasser: MUSSER,JOHN H.,US, KREFT,ANTHONY F.,US, KUBRAK,DENNIS M.,US
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creator MUSSER,JOHN H.,US
KREFT,ANTHONY F.,US
KUBRAK,DENNIS M.,US
description Heterocycles of formula (I) and their pharmaceutically acceptable salts are new, Z = N W =CHR2 when n = 0 or CR2 or CHR2 when n = 1; Y = CH2O, OCH2, CH2S, SCH2, CH2N(R2), N(R2)CH2, CON(R2) or N(R2)CO; n = 0 or 1; R1 = H, lower alkyl, lower alkoxy, lower alkanoyl, halo, CF3, NO2 or CN; R2 = H or lower alkyl; R3 = lower alkyl, lower perfluoroalkyl or perfluorophenyl, halo = F, Cl or Br; lower alkyl or alkoxy = 1-6C; lower alkanoyl = 2-6C. Specifically claimed are 3 cpds. (I) viz. N-(3-((2-quinolyl) methoxy)phenyl)ethane sulphonamide, N-(3-((2-quinolyl) methoxy) phenyl) -1-butanesulphonamide and N-(3-((2-quinolyl) methoxy) phenyl) trifluoromethane sulphonamide (Ia).
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N-(3-((2-quinolyl) methoxy)phenyl)ethane sulphonamide, N-(3-((2-quinolyl) methoxy) phenyl) -1-butanesulphonamide and N-(3-((2-quinolyl) methoxy) phenyl) trifluoromethane sulphonamide (Ia).</description><edition>4</edition><language>eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1988</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19880328&amp;DB=EPODOC&amp;CC=HU&amp;NR=T44511A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19880328&amp;DB=EPODOC&amp;CC=HU&amp;NR=T44511A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MUSSER,JOHN H.,US</creatorcontrib><creatorcontrib>KREFT,ANTHONY F.,US</creatorcontrib><creatorcontrib>KUBRAK,DENNIS M.,US</creatorcontrib><title>PROCESS FOR PRODUCING NEW ANTIALLERGIC AND ANTITHROMBOTICHETEROCYCLIC COMPOUNDS</title><description>Heterocycles of formula (I) and their pharmaceutically acceptable salts are new, Z = N W =CHR2 when n = 0 or CR2 or CHR2 when n = 1; Y = CH2O, OCH2, CH2S, SCH2, CH2N(R2), N(R2)CH2, CON(R2) or N(R2)CO; n = 0 or 1; R1 = H, lower alkyl, lower alkoxy, lower alkanoyl, halo, CF3, NO2 or CN; R2 = H or lower alkyl; R3 = lower alkyl, lower perfluoroalkyl or perfluorophenyl, halo = F, Cl or Br; lower alkyl or alkoxy = 1-6C; lower alkanoyl = 2-6C. 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Specifically claimed are 3 cpds. (I) viz. N-(3-((2-quinolyl) methoxy)phenyl)ethane sulphonamide, N-(3-((2-quinolyl) methoxy) phenyl) -1-butanesulphonamide and N-(3-((2-quinolyl) methoxy) phenyl) trifluoromethane sulphonamide (Ia).</abstract><edition>4</edition><oa>free_for_read</oa></addata></record>
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PROCESS FOR PRODUCING NEW ANTIALLERGIC AND ANTITHROMBOTICHETEROCYCLIC COMPOUNDS
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