PROCESS FOR PRODUCING NEW ANTIALLERGIC AND ANTITHROMBOTICHETEROCYCLIC COMPOUNDS

Heterocycles of formula (I) and their pharmaceutically acceptable salts are new, Z = N W =CHR2 when n = 0 or CR2 or CHR2 when n = 1; Y = CH2O, OCH2, CH2S, SCH2, CH2N(R2), N(R2)CH2, CON(R2) or N(R2)CO; n = 0 or 1; R1 = H, lower alkyl, lower alkoxy, lower alkanoyl, halo, CF3, NO2 or CN; R2 = H or lowe...

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Bibliographische Detailangaben
Hauptverfasser:	MUSSER,JOHN H.,US, KREFT,ANTHONY F.,US, KUBRAK,DENNIS M.,US
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Heterocycles of formula (I) and their pharmaceutically acceptable salts are new, Z = N W =CHR2 when n = 0 or CR2 or CHR2 when n = 1; Y = CH2O, OCH2, CH2S, SCH2, CH2N(R2), N(R2)CH2, CON(R2) or N(R2)CO; n = 0 or 1; R1 = H, lower alkyl, lower alkoxy, lower alkanoyl, halo, CF3, NO2 or CN; R2 = H or lower alkyl; R3 = lower alkyl, lower perfluoroalkyl or perfluorophenyl, halo = F, Cl or Br; lower alkyl or alkoxy = 1-6C; lower alkanoyl = 2-6C. Specifically claimed are 3 cpds. (I) viz. N-(3-((2-quinolyl) methoxy)phenyl)ethane sulphonamide, N-(3-((2-quinolyl) methoxy) phenyl) -1-butanesulphonamide and N-(3-((2-quinolyl) methoxy) phenyl) trifluoromethane sulphonamide (Ia).