PROCESS FOR PRODUCING 5-SUBSTITUTED-2-COMMA ABOVE-CHLORO-2-COMMA ABOVE-DEOXY-URIDINE AND FOR TRANSFORMING THEM TO 5-SUBSTITUTED-2-COMMA ABOVE-DEOXY-URIDINES

PROCESS FOR PRODUCING 5-SUBSTITUTED-2-COMMA ABOVE-CHLORO-2-COMMA ABOVE-DEOXY-URIDINE AND FOR TRANSFORMING THEM TO 5-SUBSTITUTED-2-COMMA ABOVE-DEOXY-URIDINES

Novel prepn. of 2'-chloro -2'-dexoxy-uridines substd. in the 5 position (III) and their conversion into 5-substd.-2'-desoxy-uridi nes (IV). In above formulae R is alkyl, substd. alkyl, vinyl or substd. vinyl gp. (1-10C) or a halogen atom. X and Y are H, alkanoyl, substd. alkanoyl, cyc...

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Hauptverfasser: RATONYI,ZOLTAN,HU, SZABOLCS,OTTONE,HU, SZAMMER,JANOS,HU, DAROCZI,IVAN,HU, GAL,TIBOR,HU, NAGY,JANOS,HU, OETVOES,LASZLO,HU, TEGYEI,ZSUZSA,HU, PAL,IVAN,HU, GAAL,GASZTON,HU
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Zusammenfassung:Novel prepn. of 2'-chloro -2'-dexoxy-uridines substd. in the 5 position (III) and their conversion into 5-substd.-2'-desoxy-uridi nes (IV). In above formulae R is alkyl, substd. alkyl, vinyl or substd. vinyl gp. (1-10C) or a halogen atom. X and Y are H, alkanoyl, substd. alkanoyl, cycloalkanoyl, substd. cyclo-alkanoyl, aroyl, substd. aroyl, heterocyclic acyl, and substd. heterocyclic gps.. - Cpds. having ethyl. n-propyl, iso-propyl vinyl or substd. vinyl gps. in the 5 position possess an antiherpetic effect.