FERMENTATIVE PROCESS FOR PRODUCING L-PROLINE

The invention relates to the microbiological industry and relates in particular to a process for the preparation of L-proline. The process according to the invention comprises cultivating mutants of microorganisms of the genus Brevibacterium which are resistant both to 3,4-dehydroproline and to an e...

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Hauptverfasser: KELESHIAN,SUSANA K.,SU, KOCHARIAN,SHAVARASH M.,SU, AKOPIAN,EDUARD M.,SU, AMBARTSUMIAN,ARTUR A.,SU, ARUSHANIAN,ALINA V.,SU, AZIZIAN,ASMIK G.,SU, KARAPETIAN,ZHANETA V.,SU
Format: Patent
Sprache:eng
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Zusammenfassung:The invention relates to the microbiological industry and relates in particular to a process for the preparation of L-proline. The process according to the invention comprises cultivating mutants of microorganisms of the genus Brevibacterium which are resistant both to 3,4-dehydroproline and to an elevated osmotic pressure of the medium and/or are incapable of breaking down and decomposing L-proline, in a nutrient medium containing sources of carbon and nitrogen, inorganic salts and growth factors for microorganisms, and subsequent isolation of the final product from the culture liquid.