MICROBIOLOGICAL PROCESS FOR PREPARING ANTHRACYCLINE DERIVATIVES

MICROBIOLOGICAL PROCESS FOR PREPARING ANTHRACYCLINE DERIVATIVES

The present application relates to a microbiological process for the preparation of compounds of the formula I < IMAGE > in which R1 and R2 are identical or different and each represent combinations of three sugar molecules, using a specific oxidoreductase. The compounds which can be prepared...

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Bibliographische Detailangaben
Hauptverfasser: ARETZ,WERNER,DE, KRAEMER,HANS P.,DE, BERSCHEID,HANS G.,DE, FEHLHABER,HANS-WOLFRAM,DE, HUBER,GERHARD,DE
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Beschreibung
Zusammenfassung:The present application relates to a microbiological process for the preparation of compounds of the formula I < IMAGE > in which R1 and R2 are identical or different and each represent combinations of three sugar molecules, using a specific oxidoreductase. The compounds which can be prepared according to the invention have cytostatic activity and can be used as pharmaceuticals.